Lycopene can inhibit cancer

1. Lycopene has strong antioxidant effect, quenching free radicals, from the source to protect the animal body from infringement.
2. The lycopene can block the tissue cell gene mutation in under the action of outside world (Seval, 2006).
3. The mechanism of oxidative damage and decreased cell membrane.
4. The induction of gap junctional intercellular communication mechanism, gap junction intercellular communication (GJIC,fruit powder) is an important way to connect and exchange information between cells and structures, most tumor cells GJIC function weak or absent, malignant transformation cells after the GJIC function significantly decreased or inhibited.Lycopene can through the GJIC to tumor cells is inhibited or destroyed communication 
5. Lycopene Softgels ,function restoration (Karas, 1999).
   The inhibition of tumor, cancer cell proliferation (Adetayo, 2005).

Lycopene in the animal feed

Rao (2000), Takeoka et al. (2001) study found that serum and tissue lycopene levels showed a significant negative correlation with the occurrence of many chronic diseases, add tomato red in animal feed element natural plant extract can effectively prevent a variety of diseases, Lycopene Oil ,the protection of animal body to avoid infringement, reduce the loss of animal husbandry.

The experiment found of lycopene

Li Hui et al (2005) test in the study of lycopene on oxidative damage in rats also obtained the same results. Matos (2000), Velmurugan (2002), Balaiya (2005), Kazim (2006) in the study of lycopene on lipid peroxidation effects of different tests are found that,Dried Apple Powder

  Lycopene can significantly reduce the degree of lipid peroxidation, protect biological membranes of mammalian and DNA against free radical( Lycopene Oil ) damage, can effectively prevent and reduce the incidence of disease.

Lycopene physical and chemical effect

Singlet oxygen and peroxyl radicals in vivo has strong activity of free radicals, lycopene can synergy by physical and chemical methods, singlet oxygen quenching and capture the excessive body and peroxide free radicals.

  Pan et al. (2004) to study the effect of lycopene on Antioxidation of rats body, test 4 weeks after (instant fruit drink powder) the detection of plasma and liver in rats SOD (SOD) activity, malondialdehyde (MDA) content, glutathione peroxidase (GSH-Px) activity and total antioxidant capacity (T-AOC), compared with the control group the experimental group rats, SOD, GSH-Px and T-AOC activity increased significantly, MDA content had significantly lower trend, that Lycopene Softgels with antioxidation function.

The free radical in the role of lycopene

Free radicals（ lycopene oil ） can stimulate the growth and differentiation of cells at low concentrations, which is protective agent cells from damage and infection.

  However, free radicals ( Lycopene Softgels )containing unpaired electrons is highly reactive, triggered a chain reaction of free radical easily at high concentrations, caused by DNA, proteins and lipids, especially polyunsaturated fatty acids macromolecules such as degeneration and crosslinking, DNA damage, biological membrane, an important structure protein and the function of protein.

  The antioxidant capacity in many of the carotenoid lycopene Astaxanthin  in the strongest, the main reason is because of its molecules containing multiple conjugated double bond and lycopene in chemistry during the regeneration effect.

That 's astaxanthin!

In 1944 the British biochemist Tisher -- first  confirmed the red substance is astaxanthin.

  Mcpherson astaxanthin is a carotenoid, since the 90's of last century, the domestic surgery circles caused great concern and has done a large number of experimental studies.

  The research results show that,astaxanthin is found to be the strongest natural antioxidants to this day , antioxidant ability is 550 times of vitamin E!

Haematococcus pluvialis's strong vitality is thanks to this layer of protective shield to astaxanthin .

Inoculation uterus for natural astaxanthin

A large number of study shows that  Haematococcus pluvialis's accumulation rate and the total production of astaxanthin is higher than the other  algae. Haematococcus astaxanthin with its esters content ratio (single monoester, diester and about 70% 5% 25%) and the ratio of aquaculture animal itself is very similar, which is the advantage of astaxanthin extraction through chemical synthesis and  the use of  phaffiarhodozyma do not possess .

  In addition, the structure of astaxanthin in haematococcuspluvialis mainly consists of 3S 3 'S type, consistent with the salmon and other aquatic organisms astaxanthin structure, and the structure of Phaffia rhodozyma astaxanthin is a 3 R type 3R.

  Haematococcus pluvialis was recognized as the best biological, production of natural astaxanthin  in nature, therefore, there's no doubt  have wide development perspective undoubtedly for using this microalgae extract astaxanthin,which has become a hot research topic in the international on the production of natural astaxanthin.

Physical and chemical properties of astaxanthin

Astaxanthin chemical name: 3, 3 '- two hydroxy -4, 4' - two keto beta carotene, cytochrome Aj067-69 CAS No: 472-61-7, a molecular formula of C40H52O4, the molecular weight of 596.86.For both ends of the hydroxyl (-OH) optical reasons,astaxanthin has the 3 different patterns of3S-3'S, 3R-3' S, 3R-3'R (also known as left-handed, meso, right) , in which a mixture of artificial synthetic astaxanthin is 3 kinds of structure of astaxanthin (sinistral dextral accounted for 25%, accounted for 25%, eliminating internal rotating about 50%), few antioxidant activity, be quite different from astaxanthin  of aquaculture organisms such as  salmon (in the trans structure -- 3S-3 S type)  .

  Astaxanthin of yeast source is 100% right-handed (3R-3'R),with part of antioxidant activity.

  The two sources of astaxanthin mainly used innon food animals and supplies coloring.Only astaxanthin of algae source is 100% L (3S-3'S) structure, with the strongest biological activity.

The ability of scavenging free radicals,astaxanthin

Natural astaxanthin antioxidative activity exceed existing antioxidants. Its ability to scavenge free radicals as follows, astaxanthin is 6000 times of the effects of vitamin C, 1000 times of vitamin E ,800 times of coenzyme Q10,1800 times of nitric oxide,3100 times of natto, 700 times of anthocyanin,100 times of the beta carotene is lycopene ,1800 times of lycopene,200 times  of Lutein, 320 times of tea polyphenols.

  Only algae and yeast , bacteria can produce astaxanthin, which higher animal cannot change the chemical structure. Natural astaxanthin has a clear characteristic, which is only one carotenoid  through the blood brain barrier .

Two ways of obtaining astaxanthin

Astaxanthin production with synthetic and biological acquisition in two ways. Synthetic astaxanthin is not only expensive, but also with significant difference of the natural astaxanthin in structure, function, application and safety etc.

  Artificial synthesis is the chemical method, which prepared from the carotenoid astaxanthin.Biological method to obtain the biological source of natural astaxanthin, in general there are 3, aquatic products processing industry waste, red yeast Phaffia rhodozyma and microalgae (mainly Haematococcus pluvialis).

  Astaxanthin can use chemical method from carotene prepared. This is the main source of astaxanthin in fish feed, the world have the capacity to synthesize production is BASF, DSM, Zhejiang NHU company Ltd.and Zhejiang pharmaceutical.

  Apart from the algae extract,as the two kind of method of the addition of shrimp waste extraction of astaxanthin producing yeast extract  is more expensive, This is why chemical synthesis approach is commonly used.