Inoculation uterus for natural astaxanthin

A large number of study shows that  Haematococcus pluvialis's accumulation rate and the total production of astaxanthin is higher than the other  algae. Haematococcus astaxanthin with its esters content ratio (single monoester, diester and about 70% 5% 25%) and the ratio of aquaculture animal itself is very similar, which is the advantage of astaxanthin extraction through chemical synthesis and  the use of  phaffiarhodozyma do not possess .

  In addition, the structure of astaxanthin in haematococcuspluvialis mainly consists of 3S 3 'S type, consistent with the salmon and other aquatic organisms astaxanthin structure, and the structure of Phaffia rhodozyma astaxanthin is a 3 R type 3R.

  Haematococcus pluvialis was recognized as the best biological, production of natural astaxanthin  in nature, therefore, there's no doubt  have wide development perspective undoubtedly for using this microalgae extract astaxanthin,which has become a hot research topic in the international on the production of natural astaxanthin.

3 kinds of biological source of natural astaxanthin

• Marine waste extract

That is extracted from the aquatic product processing industry waste, all kinds of seafood processing waste.

• Yeast extract

Colonies bacterial of phaffia rhodozyma in yeast produce astaxanthin and other carotenoids turning red.Carotenoids are uniformly distributed in cell lipids. The average content of astaxanthin by natural phaffia rhodozyma is 0.40%. Therefore, red yeast Phaffia rhodozyma  for overproducing astaxanthin attracted much attention .

• Algae extract

Natural astaxanthin  mainly from haematococcus pluvialis. Haematococcus pluvialis in nature in the main growth distribution is formed in the small pond and small temporary blisters after the rain water ,which is microorganisms synthesis and accumulation of  the most astaxanthin in nature.

Biological acquisition of astaxanthin

In astaxanthin artificial synthetic and biological acquisition two ways, we look at access to biological pathway.

• biological acquisition

  In addition to the artificial chemical synthesis, natural astaxanthin biological sources generally has 3 kinds,aquatic products processing industry waste, red yeast Phaffia rhodozyma (Phaffia rhodozyma) and microalgae (Haematococcus pluvialis).

Among them, the astaxanthin content of waste in the lower, and the extraction of high cost, not suitable for large-scale production.

  The average content of  natural astaxanthin by phaffiarhodozyma also is only 0.40%. In contrast, Haematococcus pluvialis in astaxanthin content is up to 1.5% ~ 3%, so it is regarded as the product of natural astaxanthin concentration .

Physical and chemical properties of astaxanthin

Astaxanthin chemical name: 3, 3 '- two hydroxy -4, 4' - two keto beta carotene, cytochrome Aj067-69 CAS No: 472-61-7, a molecular formula of C40H52O4, the molecular weight of 596.86.For both ends of the hydroxyl (-OH) optical reasons,astaxanthin has the 3 different patterns of3S-3'S, 3R-3' S, 3R-3'R (also known as left-handed, meso, right) , in which a mixture of artificial synthetic astaxanthin is 3 kinds of structure of astaxanthin (sinistral dextral accounted for 25%, accounted for 25%, eliminating internal rotating about 50%), few antioxidant activity, be quite different from astaxanthin  of aquaculture organisms such as  salmon (in the trans structure -- 3S-3 S type)  .

  Astaxanthin of yeast source is 100% right-handed (3R-3'R),with part of antioxidant activity.

  The two sources of astaxanthin mainly used innon food animals and supplies coloring.Only astaxanthin of algae source is 100% L (3S-3'S) structure, with the strongest biological activity.

The ability of scavenging free radicals,astaxanthin

Natural astaxanthin antioxidative activity exceed existing antioxidants. Its ability to scavenge free radicals as follows, astaxanthin is 6000 times of the effects of vitamin C, 1000 times of vitamin E ,800 times of coenzyme Q10,1800 times of nitric oxide,3100 times of natto, 700 times of anthocyanin,100 times of the beta carotene is lycopene ,1800 times of lycopene,200 times  of Lutein, 320 times of tea polyphenols.

  Only algae and yeast , bacteria can produce astaxanthin, which higher animal cannot change the chemical structure. Natural astaxanthin has a clear characteristic, which is only one carotenoid  through the blood brain barrier .

Two ways of obtaining astaxanthin

Astaxanthin production with synthetic and biological acquisition in two ways. Synthetic astaxanthin is not only expensive, but also with significant difference of the natural astaxanthin in structure, function, application and safety etc.

  Artificial synthesis is the chemical method, which prepared from the carotenoid astaxanthin.Biological method to obtain the biological source of natural astaxanthin, in general there are 3, aquatic products processing industry waste, red yeast Phaffia rhodozyma and microalgae (mainly Haematococcus pluvialis).

  Astaxanthin can use chemical method from carotene prepared. This is the main source of astaxanthin in fish feed, the world have the capacity to synthesize production is BASF, DSM, Zhejiang NHU company Ltd.and Zhejiang pharmaceutical.

  Apart from the algae extract,as the two kind of method of the addition of shrimp waste extraction of astaxanthin producing yeast extract  is more expensive, This is why chemical synthesis approach is commonly used.

Lycopene and seabuckthorn fruit oil cooperation

Seabuckthorn fruit oilas the filler of vegetable oil  in lycopene soft capsule,contains a lot of and antioxidants,which can directly effect the body and prevent the body peroxidation, accelerating the elimination of peroxide of free radical in vivo , with strong antioxidant effect.

  Lycopene and seabuckthorn fruit oil cooperation, has anti radiation effect. And it can improve the result of radiation caused by the female endocrine disorders, symptoms of abnormal menstruation, complexion dark and gloomy, yellow brown spots, to balance the endocrine, cosmetic removing chloasma role.

Function test of lycopene

1. Function test of lycopene displays,beyond  strong radiation, lycopene can significantly increase the number of white blood cells in the blood of the human body and the effective protection of human SOD.Therefore, lycopene has the functions of preventing and anti injury effects of ultraviolet radiation on the skin.
2. Anti-tumor and anti mutagenesis effect. One of the physiological mechanism of tumor formation is the tissue cells in the outside world under the function of the gene mutation, lycopene can block this process, anti-cancer effect change
3. Cardiovascular protective effect. Lycopene can protect low density lipoprotein against oxidative damage, which can prevent cardiovascular disease.
4. Lycopene on prostate disease, breast disease has inhibitory effect which has been acknowledged.